منابع مشابه
False-negative synovial alpha-defensin
We present a case of chronic periprosthetic hip infection diagnosed using the Musculoskeletal Infection Society criteria as the gold standard. The alpha-defensin test was falsely negative. The diagnostic workup of the patient is detailed, along with a discussion regarding the potential reasons behind the misleading alpha-defensin results. To our knowledge, this is the first reported case of a f...
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متن کاملHow Reliable Is the Alpha-defensin Immunoassay Test for Diagnosing Periprosthetic Joint Infection? A Prospective Study
BACKGROUND A key issue in the treatment of periprosthetic joint infection (PJI) is the correct diagnosis. The main problem is lack of diagnostic tools able to diagnose a PJI with high accuracy. Alpha-defensin has been proposed as a possible solution, but in the current literature, there is a lack of independent validation. QUESTIONS/PURPOSES We performed a prospective study to determine (1) w...
متن کاملThe Alpha-defensin Test for Periprosthetic Joint Infection Responds to a Wide Spectrum of Organisms
BACKGROUND The alpha-defensin test has been previously demonstrated to be highly accurate in the diagnosis of prosthetic joint infection (PJI), nearly matching the Musculoskeletal Infection Society definition for PJI. However, the relationship between alpha-defensin levels and differing infecting organism has not yet been investigated. QUESTIONS/PURPOSES The purpose of this study is to descri...
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ژورنال
عنوان ژورنال: Arthroplasty Today
سال: 2017
ISSN: 2352-3441
DOI: 10.1016/j.artd.2017.05.006